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More PFI Patients Undergo Surgery Than Anticipated

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PUBLISHED
March 28, 2025
A close-up of a foot experiencing relief from the pain of Plantar Fibromatosis (PFI), a rare connective tissue disorder.

Clinical Characteristics Of Plantar Fibromatosis Derived From Transcription Notes

This poster was originally presented at the American Podiatric Medical Association Annual Meeting, August 8-11, 2024, in Washington, DC.

 

Authors: Jill Davis, MS; David Hurley, MD; Jennifer Black-Shinn, PhD, MPH; Fernando Otalora, BA; Esteban Masuelli, BA; and Eddie Davis, DPM

Affiliations: Amplity, Langhorne, PA, USA; Endo USA Inc, Malvern, PA; South Texas Podiatrist, San Antonio, TX

 

 

Introduction

The study objectives were to use natural language processing (NLP) of unstructured medical transcription records to describe the clinical characteristics of plantar fibromatosis (PFI); the pain associated with PFI + the treatment approaches used for patients with PFI.

 

Methods

  • This was a cross-sectional, retrospective study using the Amplity AnswerY™ (formerly known as Amplity Insights) unstructured medical transcription database encompassing approximately 55 million records from more than 28 million patients
  • NLP logic was leveraged to identify PFI patients and describe demographic, clinical + treatment characteristics
  • Included patients had ≥1 record with a diagnostic mention of PFI, fibroma in the plantar region, or Ledderhose disease within a transcription record between January 1, 2015, and July 31, 2022; the overall PFI cohort included 2273 patients

 

Results

  • Records from 1163 patients (51.2%) included mention of PFI-specific symptoms. The most reported symptoms were swelling/edematous (42.6%) and tenderness (30.9%). In addition, 22.5% of patients reported deformity/rigidity, and 8.7% reported having contractures

 

Percentages Of Patients Reporting PFI-Specific Symptoms

  • PFI-specific foot pain recorded in 65.2% (1,482/2,273) of patients in the overall PFI cohort, with 88.5% recorded as moderate or severe

 

Percentages of patients reporting PFI-specific foot pain.

  • Confirmed PFI-specific surgery was defined as any mention of specific procedures (ie, local excision, wide excision, or complete fasciectomy) in proximity to the words “plantar,” “nodule,” “plantar fibromatosis,” “fibroma,” or “masses,” and was undertaken by 10.9% (93/854) of patients
  • The most frequently reported quality-of-life impairments were ambulation/mobility/gait issues (44.0%), joint pain (36.1%), and difficulty sleeping

 

Quality of Life is impacted for patients with PFI. 

 

Conclusions

  • Findings from AnswerY unstructured electronic medical transcription records demonstrate that patients with PFI appear to suffer from both direct + indirect symptom burden
  • Almost two-thirds of patients in the overall cohort reported PFI-specific foot pain with nearly 90% of these describing the pain as moderate or severe
  • Although conservative, nonsurgical treatment options were recorded, a higher-than-expected percentage of patients underwent surgical treatment

 

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PUBLISHED •
March 28, 2025

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